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降钙素联合臭氧、透明质酸钠对膝关节炎患者Lequesne评分及关节指数积分的影响

时间:2022-03-13 09:42:07 公文范文 浏览量:

  [摘要] 目的 探讨降钙素联合臭氧、透明质酸钠对膝骨关节炎患者Lequesne评分及关节指数积分的影响,为膝关节炎患者临床治疗提供理论参考。方法 方便选择2015年1月—2017年7月该院收治的膝关节炎患者200例,随机分为两组,每组100例;在常规治疗的基础上,对照组患者采用臭氧、透明质酸钠治疗,观察组患者在对照组的基础上加用降钙素治疗;采用膝骨性关节炎严重性指数(Lequesne)比较两组患者膝关节炎治疗情况,根据治疗后患者关节指数积分进步情况对评价临床疗效。结果 治疗后,两组患者Lequesne评分均降低,且观察组(6.37±1.33)分低于对照组(8.89±1.38)分;观察组治疗总有效率(96.0%)明显高于对照组(81.0%),差异有统计学意义(P<0.05)。结论 降钙素联合医用臭氧、透明质酸钠能够有效降低膝关节炎患者Lequesne评分,疗效确切,临床推广价值高。
  [关键词] 降钙素;臭氧;透明质酸钠;Lequesne评分;临床疗效
  [中图分类号] R684 [文献标识码] A [文章编号] 1674-0742(2018)01(c)-0015-03
  [Abstract] Objective This paper tries to investigate the effects of calcitonin combined with ozone and sodium hyaluronate on Lequesne score and joint index score in patients with knee osteoarthritis, and to provide theoretical reference for the clinical treatment of patients with knee osteoarthritis. Methods 200 cases of patients with knee osteoarthritis from January 2015 to July 2017 in this hospital were conveient selected, and were randomly divided into two groups, with 100 patients each group; On the basis of conventional treatment, the control group was given ozone and sodium hyaluronate for treatment, and the observation group was treated with calcitonin on the basis of control group; The knee osteoarthritis severity index (Lequesne) was compared for the treatment of knee arthritis in two groups, according to the progress of the patients’ joint index scores, the clinical efficacy was evaluated. Results After treatment, Lequesne scores decreased in both groups, and the scores of observation group (6.37±1.33) points was lower than control group (8.89±1.38) points, the total effective rate of observation group(96.0%) was significantly higher than control group (81.0%), the difference was statistically significant(P<0.05). Conclusion Calcitonin combined with medical ozone and sodium hyaluronate can effectively reduce the Lequesne score in patients with knee osteoarthritis, the curative effect is exact, the clinical popularization value is high.
  [Key words] Calcitonin; Ozone; Sodium hyaluronate; Lequesne score; Clinical efficacy
  膝關节炎是指膝骨性关节炎,是一种以退行性病理改变(包含关节软骨代谢紊乱和降解等)为基础的慢性关节炎性疾病,在中老年群体中发病率较高,60岁以上人群的发病率高达42.8%,在75岁人群中发病率高达80.0%,是造成患者肢体残疾的重要病因之一[1]。随着我国人口老龄化的加重,世界卫生组织预测我国将成为膝关节炎数量最多的国家之一,且由于膝关节炎致残率较高,会使患者失去劳动能力,对患者正常生活造成负担,因此,膝关节炎的治疗十分重要[2]。膝关节炎致病原因多,在临床治疗上存在较大阻碍,目前临床上以非药物保守治疗及手术治疗为主,以求达到消炎、缓解关节疼痛的作用。该研究探讨该院2015年1月—2017年7月期间100例服用降钙素联合臭氧、透明质酸钠的膝关节炎患者与100例采用臭氧、透明质酸钠治疗的膝关节炎患者治疗前后膝骨性关节炎严重性指数(Lequesne)评分及关节指数积分的比较,现报道如下。
  1 资料与方法

推荐访问:膝关节 臭氧 关节 患者 评分

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